The hormone that holds key to HIV cure may also shift the balance of the immume system to activation. By increasing the Hormone IL-7 during therapy, you could shut down the SOCS3 expression giving rise to the TH1 Phenotype needed for the immune response.
Source:The hormone that holds key to HIV cure
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“The researchers increased levels of the hormone IL-7, the gene SOCS-3 “switched off” and the trial mice were able to gradually eliminate the HIV from their bodies, says the main study published in the February 4 2011 issue of the journal Cell.”
SOCS3 inhibits TH1 Phenotype
SOCS3 inhibits TH17 Phenotype
SOCS3 activates TH2 phenotype
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Is it possible by the raising the IL-7 concentration, pushes the T-cell differentiation towards the TH1/TH17 phenotypes. If that is the case, the oncologists have another knob to turn to involke an immune response.
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“It is not the strongest of the species that survives, nor the most intelligent, but the one most responsive to change.”
~Charles Darwin~
Take Care,
Jimmy B
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