• Mislead the public/Government about the Ipilimumab Shortage
• Stopped the compassionate drug use on 9/12/2008
• Continued to create/open clinical trials with Ipilimumab
• Increased their stock dividend as of February 2010
• Continuously turn away Melanoma patients that did not qualify for their trials
As a Melanoma Patient and a survivor, I believe BMS is the New Dr. Kevorkian.
They are killing cancer patients that have no other alternative and Anti-CTLA-4 blockage was their last hope.
“Scientists have discovered that an important mechanism for down regulation is mediated by a molecule called CTLA-4. The T cells are initially activated by other immune cells, called dendritic cells, that display the foreign, or cancerous, antigens to the T cells and instruct them to be active. After this initial activation, CTLA-4 appears on the surface of the T cells, and when CTLA-4 interacts with the dendritic cells, the next set of signals are to turn the response down, or even off. CTLA-4 is part of a regulatory mechanism that normally protects the body from immune overreactions, but when it is expressed in the presence of mutant cancer cells the result is tumor evasion of the immune response. Ipilimumab is an antibody that blocks CTLA-4, releasing this safety brake, and allowing the immune response to have a stronger anti-tumor effect.”
Source: Oregon Health and Science University
With Bristol-Meyer Squibb not allowing compassionate drug use, they are invoking a death sentence on the cancer patient. Since Pfizer pulled out of this therapy due to the fact they wanted the drug as a monotherapy when the scientific data suggests that a combination of this drug would have better results. So BMS now has a monopoly on this drug and will be able to charge a great deal for it even though it is made in thousands of units per batch. When will the FDA coming in and do what is ethical for the country?
We cannot let a deceitful and greedy company control our destiny.
“In our daily life, we encounter people/companies who are deceitful, intent only on satisfying their own needs. There is so much anger, distrust, greed, and pettiness that we are losing our capacity to work well together to do what is ethically right.”