Take a look at this updated graphic. Notice that the upregulation of the CTLA-4 receptor is at it's max about 3 days after T-cell activation. These receptors must be blocked to surpress the Treg function.
“It is not the strongest of the species that survives, nor the most intelligent, but the one most responsive to change.”
~Charles Darwin~
Take Care,
Jimmy B
No comments:
Post a Comment