Jimmy B. about your last post 8-4-2009 ..Timing and Tregs.Melanoma.Jim Breitfeller

Jimmy B. about your last post

Posted by JerryfromFauq at 12:02 on Tue, Aug 04, 2009 [Show other posts by JerryfromFauq]
I copied it and emailed your last post here to my Medical Oncologist at UVA. Below is his response. Keep up the good work.
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Dear Mr. Ellis,
Thanks for this information. The impact of IL-2 on regulatory T-cells has long been known from animal studies. I am very interested to see this approach to the phenomenon and the proposal to regulate regulatory T-cell action. As you know, antibodies now exist which inhibit regulatory T-cell activity (ipilimumab and tremilimumab).

I think this timing approach has merit.
Thanks again.
Geoff

Weiss, Geoffrey R
From: tjellis [mailto:tjellis]
Sent: Saturday, August 01, 2009 7:14 PM

To: Weiss, Geoffrey ,
Subject: IL-2 administration increases CD4 + CD25(hi) Foxp3+ regulatory T cells in cancer

The following post was provided by a medical researcher that has Melanoma and posts on the MPIP.org.

He has some interesting theories from his research and experience about the timing of treatments that is posted on his website.
IL-2 administration increases CD4 + CD25(hi) Foxp3+ regulatory T cells in cancer


Take Care,

Jimmy B