Insights from molecular pathology
"Another key to progress may come from the field of molecular pathology. “We used to think that melanoma was a single entity,” said Victor Prieto, M.D., Ph.D., a professor in the Department of Pathology. “But in the last five years, we have come to realize that isn’t the case at all.”
What investigators have recently realized is that the four major subtypes of melanoma, long-recognized as superficial spreading, nodular, lentigo maligna, and acral lentiginous melanoma, each have a different genetic profile and further, that this genetic profile can be linked to a phenotype. According to Dr. Prieto, this is an important insight because targeted therapies are specific to particular proteins."
Taken from MD Anderson -oncolog
Guess what I started asking that question to us patients on Carepages last year, I can recall.
Do you know what type of Melanoma you have??????? If you don't, please find out. It is another piece of the puzzle in the melanoma Maze.
I do, it is Nodular Melanoma, the most Deadliest. That is because it grows rapidly in the vertical direction. Down, Down, into the lymphatic system and eventually into the blood stream.
Jimmy B
Check out the link below....
ReplyDeletehttp://www.medscape.com/viewarticle/584180
It's not any information that you don't already know, but I thought you might like the CTLA-4 picture/graphic about 1/2 to 3/4's down the page.
I'm a little bit more "simple minded" and pictures help me understand "science lingo" a little easier.
Enjoy,
Teri2007
Teri, I have the pics , I was trying to get permission to post them.
ReplyDelete